-22%
4X Tested - ISO 17025
Sleep Peptide

DSIP

Certificate of Analysis

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide studied for its role in sleep regulation, stress modulation, and neuroendocrine function in preclinical research models.

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Description

What is DSIP?

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated from rabbit brain tissue in 1977. It consists of nine amino acids and was named for its ability to induce delta (slow-wave) sleep in animal models when administered to the brain.

DSIP is found in both the brain and peripheral tissues, and acts as a neuromodulator with effects on multiple physiological systems. Beyond sleep regulation, it has been studied for stress modulation, pain perception, hormone regulation, and antioxidant activity.

Despite its name, the exact mechanisms by which DSIP influences sleep architecture remain an active area of research. It appears to modulate several neurotransmitter and neuroendocrine systems rather than acting through a single sleep-specific pathway.

DSIP is not approved by the FDA for any medical use. All products are sold strictly for laboratory and research purposes only.


Research Applications

Areas of Investigation
Sleep

Sleep Architecture Research

Studied for its ability to promote delta (slow-wave) sleep and normalize disrupted sleep patterns in animal models.
Stress

Stress & Cortisol Modulation

Investigated for its effects on the hypothalamic-pituitary-adrenal axis and stress hormone regulation.
Hormonal Balance

Neuroendocrine Function

Researched for modulatory effects on multiple hormone systems including LH, GH, and cortisol.
Pain Research

Pain & Nociception Research

Explored in preclinical models for analgesic properties and modulation of pain perception pathways.

Compound Profile

Technical specifications
What is DSIP?

Molecular Profile


Sequence
WAGGDASGE
Molecular Formula
C₃₅H₄₈N₁₀O₁₅
Molecular Weight
848.81 g/mol
Appearance
White lyophilized powder

Form

Lyophilized (freeze-dried)
Handling & Shelf Life Guidelines

Storage & Stability


Storage (Pre-Reconstitution)

Store below -18°C, desiccated, away from light and moisture.
Storage (Post-Reconstitution)
Refrigerate at 2–8°C. For longer storage, aliquot and store below -18°C. Avoid freeze-thaw cycles.
Shelf Life
24 months from date of manufacture when stored as directed
Sensitivity Notes
Sensitive to heat, light, and moisture. Keep sealed until use.
Compliance & Clinical Overview

Regulatory & Research Status


FDA Status
Not approved for human use.
WADA Classification
Not currently specifically listed as a prohibited substance.
Clinical Trial Status
Preclinical and early clinical studies on sleep architecture, stress response, pain modulation, and neuroendocrine regulation.
Published Studies
Preclinical and early clinical studies on sleep architecture, stress response, pain modulation, and neuroendocrine regulation.
Research Disclaimer
For laboratory and research purposes only. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics
99.00%
Purity
Variant
DSIP
Lot #
DSIP50GL01
Labelled
5mg
Actual
5.13mg
Tested
6/24/2026
View COA
(opens in a new tab)
99.73%
Purity
Variant
DSIP
Lot #
GLZ-DSIP-5MG-A
Labelled
5mg
Actual
4.83mg
Tested
3/29/2026
View COA
(opens in a new tab)

Frequently Asked Questions

Common questions about DSIP research