Thymosin A-1
-12%
4X Tested - ISO 17025
99.78% View COA
Immune Peptide

Thymosin A-1

Certificate of Analysis

Thymosin Alpha-1 is a naturally occurring 28-amino acid peptide derived from the thymus gland, studied for its immunomodulatory effects including T-cell maturation and immune system regulation.

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Description

What is Thymosin A-1?

Thymosin Alpha-1 (Tα1) is a naturally occurring 28-amino acid peptide originally isolated from thymic tissue. It is a key component of Thymosin Fraction 5, a partially purified extract from the thymus gland that was first characterized in the 1970s.

Tα1 plays a central role in immune system regulation, primarily through its effects on T-cell maturation and differentiation. It acts on toll-like receptors (TLR2, TLR9) on dendritic cells and enhances the immune system’s ability to respond to infections and tumors.

A synthetic version of Tα1 has been approved in over 35 countries for the treatment of hepatitis B and C, and as an immune adjuvant. It has not received FDA approval, though it has received orphan drug designation.

Research-grade Thymosin Alpha-1 is sold strictly for laboratory and research purposes only.

Research Applications

Areas of Investigation
Immunity

T-Cell Maturation & Immunity

Studied for its role in promoting T-cell differentiation and enhancing adaptive immune responses through toll-like receptor activation.
Infection

Infectious Disease Research

Investigated and approved in multiple countries as an adjunct treatment for chronic hepatitis B and C infections.
Cancer Research

Cancer Immunology

Explored as an immunotherapy adjuvant to enhance anti-tumor immune responses in combination with other treatments.
Vaccine Research

Vaccine Enhancement

Studied for its ability to improve vaccine efficacy by enhancing dendritic cell function and antigen presentation.

Compound Profile

Technical specifications
What is Thymosin A-1?

Molecular Profile

Sequence
Ac-SDAAVDT SSEITTKDLK EKKEVVEEAEN
Molecular Formula
C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight
3,108.28 g/mol
Appearance
White lyophilized powder

Form

Lyophilized (freeze-dried)
Handling & Shelf Life Guidelines

Storage & Stability

Storage (Pre-Reconstitution)

Store below -18°C, desiccated, away from light and moisture.
Storage (Post-Reconstitution)
Refrigerate at 2–8°C. For longer storage, aliquot and store below -18°C. Avoid freeze-thaw cycles.
Shelf Life
24 months from date of manufacture when stored as directed
Sensitivity Notes
Sensitive to heat, light, and moisture. Keep sealed until use.
Compliance & Clinical Overview

Regulatory & Research Status

FDA Status
Not FDA approved. Approved in 35+ countries as a brand name for hepatitis B/C and as immune adjuvant. Has FDA orphan drug designation.
WADA Classification
Not currently listed as a prohibited substance.
Clinical Trial Status
Hundreds of published studies on immune modulation, T-cell biology, vaccine adjuvancy, and infectious disease.
Published Studies
Hundreds of published studies on immune modulation, T-cell biology, vaccine adjuvancy, and infectious disease.
Research Disclaimer
For laboratory and research purposes only. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics
99.10%
Purity
Variant
Thymosin Alpha-1
Lot #
GL-2609-041
Labelled
10mg
Actual
10.44mg
Tested
9/21/2026
View COA
(opens in a new tab)
99.78%
Purity
Variant
Thymosin Alpha-1
Lot #
TA110-GL-01
Labelled
10mg
Actual
10.26mg
Tested
7/26/2026
View COA
(opens in a new tab)
99.69%
Purity
Variant
Thymosin Alpha-1
Lot #
GLZ-THYMOSIN-ALPHA-1-10MG-A
Labelled
10mg
Actual
9.46mg
Tested
3/29/2026
View COA
(opens in a new tab)

Frequently Asked Questions

Common questions about Thymosin A-1 research