Glutathione
-20%
4X Tested - ISO 17025
99.80% View COA
Master Antioxidant

Glutathione

Certificate of Analysis

Glutathione is a naturally occurring tripeptide and the body’s most abundant intracellular antioxidant, studied for its roles in detoxification, oxidative stress reduction, and cellular protection in preclinical research.

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Description

What is Glutathione?

Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a naturally occurring tripeptide composed of three amino acids: glutamine, cysteine, and glycine. It is synthesized intracellularly in nearly every cell of the human body and serves as the most abundant low-molecular-weight thiol antioxidant in living tissue.

Glutathione exists in two primary states: reduced (GSH), the active antioxidant form, and oxidized (GSSG), formed after neutralizing a free radical. The GSH/GSSG ratio is a key biomarker of cellular oxidative status, with higher GSH/GSSG ratios associated with healthier cellular environments.

In research, glutathione has been studied extensively for its central role in phase II liver detoxification, neutralization of reactive oxygen species, regeneration of other antioxidants including vitamin C and vitamin E, and conjugation of xenobiotics for elimination. Glutathione levels naturally decline with age, oxidative stress, and chronic disease, making it a peptide of significant interest in research on aging, hepatic function, and cellular resilience.”

Research Applications

Areas of Investigation
Oxidative Defense

Cellular Antioxidant Defense

The most abundant intracellular antioxidant in human cells, glutathione neutralizes reactive oxygen species and protects cellular components from oxidative damage at the molecular level.
Hepatic

Detoxification Pathways

A central component of phase II liver detoxification, glutathione conjugates with toxins, heavy metals, and metabolic byproducts to facilitate their elimination from the body.
Immunity

Immune & Aging Research

Studied for its roles in lymphocyte function, inflammatory regulation, and the decline in cellular GSH levels associated with chronological aging and age-related disease.
Energy

Mitochondrial Support

Researched for its function in protecting mitochondrial membranes from oxidative damage and supporting cellular energy production in models of metabolic stress.

Compound Profile

Technical specifications
What is Glutathione?

Molecular Profile

Sequence
γ-L-Glu-L-Cys-Gly
Molecular Formula
C₁₀H₁₇N₃O₆S
Molecular Weight
307.32 g/mol
Appearance
White lyophilized powder

Form

Lyophilized (freeze-dried)
Handling & Shelf Life Guidelines

Storage & Stability

Storage (Pre-Reconstitution)

Store below -18°C, desiccated, away from light and moisture.
Storage (Post-Reconstitution)
Refrigerate at 2–8°C and use within 7 days of reconstitution. Glutathione oxidizes readily in solution; minimize exposure to air and use promptly.
Shelf Life
24 months from date of manufacture when stored as directed
Sensitivity Notes
Highly sensitive to oxidation. The reduced (GSH) form readily converts to the oxidized (GSSG) form on exposure to air, light, or heat. Store and handle under inert atmosphere when possible.
Compliance & Clinical Overview

Regulatory & Research Status

FDA Status
Approved as an oral dietary supplement and as an injectable in some pharmaceutical formulations (used clinically in hepatic conditions in certain countries). Sold here strictly as a research chemical.
WADA Classification
Not currently listed as a prohibited substance.
Clinical Trial Status
Thousands of published studies on glutathione's role in antioxidant defense, hepatic detoxification, immune modulation, and cellular aging.
Published Studies
Thousands of published studies on glutathione's role in antioxidant defense, hepatic detoxification, immune modulation, and cellular aging.
Research Disclaimer
For laboratory and research purposes only. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics
99.77%
Purity
Variant
Glutathione
Lot #
GLZ-GLUTATHIONE-600MG-A
Labelled
600mg
Actual
564.09mg
Tested
5/11/2026
View COA
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99.80%
Purity
Variant
Glutathione
Lot #
BLUTA600MGB
Labelled
600mg
Actual
619.03mg
Tested
9/3/2026
View COA
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Frequently Asked Questions

Common questions about Glutathione research