-20%
4X Tested - ISO 17025
Metabolic Peptide

GLP-2 TZ

Certificate of Analysis

GLP-2 TZ is a 39-amino acid dual GIP/GLP-1 receptor agonist developed for metabolic research, studied for its effects on glucose regulation, insulin sensitivity, and body weight reduction.

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Description

What is GLP-2 TZ?

GLP-2 TZ is a synthetic 39-amino acid peptide that acts as a dual agonist of both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor, earning it the designation “twincretin.”

The peptide features non-coded amino acid substitutions that protect it from enzymatic degradation, and a C-20 fatty diacid moiety that enables once-weekly dosing by extending its half-life to approximately 5 days.

GLP-2 TZ has been approved by the FDA under multiple brand names. In clinical trials, it demonstrated significant reductions in HbA1c and body weight, often exceeding results seen with GLP-1 receptor agonists alone.

Research-grade GLP-2 TZ is not equivalent to FDA-approved formulations and is sold strictly for laboratory and research purposes only.


Research Applications

Areas of Investigation
Dual Action

Dual Incretin Signaling

Studied as the first dual GIP/GLP-1 receptor agonist, activating both incretin pathways for synergistic metabolic effects.
Weight Loss

Body Weight Reduction

Demonstrated significant weight loss in large-scale clinical trials, with some participants achieving over 20% body weight reduction.
Blood Sugar

Glucose & Insulin Research

Evaluated for robust glucose-lowering effects and improvements in insulin sensitivity through dual receptor activation.
Liver Health

Liver & Lipid Research

Under investigation for effects on non-alcoholic steatohepatitis (NASH) and improvements in lipid profiles.

Compound Profile

Technical specifications
What is GLP-2 TZ?

Molecular Profile


Sequence
YXEGTFTSDY SI xLLDKK* AQXAFIEYLLEG GPSSGAPPPS NH₂
Molecular Formula
C₂₂₅H₃₄₈N₄₈O₆₈
Molecular Weight
4,813.45 g/mol
Appearance
White lyophilized powder

Form

Lyophilized (freeze-dried)
Handling & Shelf Life Guidelines

Storage & Stability


Storage (Pre-Reconstitution)

Store below -20°C, desiccated, away from light and moisture.
Storage (Post-Reconstitution)
Refrigerate at 2–8°C. For longer storage, aliquot and store below -18°C. Avoid freeze-thaw cycles.
Shelf Life
24 months from date of manufacture when stored as directed
Sensitivity Notes
Sensitive to heat, light, and moisture. Keep sealed until use.
Compliance & Clinical Overview

Regulatory & Research Status


FDA Status
FDA-approved as various brand names. Research-grade peptide is not equivalent to approved formulations.
WADA Classification
Not currently prohibited by WADA (subject to change).
Clinical Trial Status
Hundreds of published studies covering glucose metabolism, weight management, cardiovascular outcomes, and liver disease.
Published Studies
Hundreds of published studies covering glucose metabolism, weight management, cardiovascular outcomes, and liver disease.
Research Disclaimer
Research-grade product is for laboratory purposes only. Not equivalent to FDA-approved formulations. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics
99.42%
Purity
Variant
GLP-2 TZ
Lot #
GL-2TZ-30MG
Labelled
30mg
Actual
31.75mg
Tested
10/08/2026
View COA
(opens in a new tab)
99.91%
Purity
Variant
GLP-2 TZ
Lot #
GL-2609-014
Labelled
10mg
Actual
10.66mg
Tested
9/21/2026
View COA
(opens in a new tab)
99.75%
Purity
Variant
GLP-2 TZ
Lot #
GLP2TZ10-GL01
Labelled
10mg
Actual
10.65mg
Tested
6/24/2026
View COA
(opens in a new tab)
99.28%
Purity
Variant
GLP-2 TZ
Lot #
GLP2TZ30-GL01
Labelled
30mg
Actual
30.67mg
Tested
6/24/2026
View COA
(opens in a new tab)
99.73%
Purity
Variant
GLP-2 TZ
Lot #
GLZ-GPL2-TZ-10MG-A
Labelled
10mg
Actual
9.94mg
Tested
3/29/2026
View COA
(opens in a new tab)

Frequently Asked Questions

Common questions about GLP-2 TZ research