GLP1-SM 10mg Certificate of Analysis 12-11-25

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Metabolic Peptide

GLP-1 SM

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GLP-1 SM is a 31-amino acid GLP-1 receptor agonist originally developed for type 2 diabetes, widely studied for its effects on glucose regulation, appetite suppression, and body weight reduction.

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Description

What is GLP-1 SM?

GLP-1 SM is a synthetic peptide composed of 31 amino acids that shares 94% structural similarity with native human GLP-1 (glucagon-like peptide-1). GLP-1 SM is one of the most extensively studied incretin-based therapies in modern medicine.

The peptide features two amino acid substitutions and a C-18 fatty acid side chain that extends its half-life to approximately 7 days, compared to just 1.5 minutes for native GLP-1. This allows for once-weekly administration in clinical settings.

Semaglutide has been approved by the FDA under multiple brand names for type 2 diabetes and chronic weight management. It works by activating the GLP-1 receptor, which stimulates insulin secretion, suppresses glucagon release, delays gastric emptying, and reduces appetite.

Research-grade GLP-1 SM sold as a lyophilized peptide is not equivalent to FDA-approved formulations and is sold strictly for laboratory and research purposes only.

Research Applications

Areas of Investigation

Blood Sugar

Glucose Regulation

Extensively studied for its ability to stimulate glucose-dependent insulin secretion and suppress glucagon release through GLP-1 receptor activation.

Weight Loss

Body Weight & Appetite

Demonstrated significant weight reduction in large-scale clinical trials through appetite suppression and delayed gastric emptying.

Heart Health

Cardiovascular Research

Evaluated in clinical trials for reduction of major adverse cardiovascular events in patients with type 2 diabetes.

Metabolism

Metabolic Syndrome

Studied for broad metabolic effects including improvements in blood pressure, lipid profiles, and inflammatory markers.

Compound Profile

Technical specifications

What is GLP-1 SM?

Molecular Profile

Sequence

HXEGTFTSD VSSYLEGQAAK *EFIAWLVRGRG

Molecular Formula

C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight

4,113.58 g/mol

Appearance

White lyophilized powder

Form

Lyophilized (freeze-dried)

Handling & Shelf Life Guidelines

Storage & Stability

Storage (Pre-Reconstitution)

Store below -18°C, desiccated, away from light and moisture.

Storage (Post-Reconstitution)

Refrigerate at 2–8°C. For longer storage, aliquot and store below -18°C. Avoid freeze-thaw cycles.

Shelf Life

24 months from date of manufacture when stored as directed

Sensitivity Notes

Sensitive to heat, light, and moisture. Keep sealed until use.

Compliance & Clinical Overview

Regulatory & Research Status

FDA Status

FDA-approved as various brand names. Research-grade peptide is not equivalent to approved formulations.

WADA Classification

Not currently prohibited by WADA (subject to change).

Clinical Trial Status

One of the most studied peptides in clinical medicine with hundreds of published studies across metabolic, cardiovascular, and neurological research.

Published Studies

One of the most studied peptides in clinical medicine with hundreds of published studies across metabolic, cardiovascular, and neurological research.

Research Disclaimer

Research-grade product is for laboratory purposes only. Not equivalent to FDA-approved formulations. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics

99.65%

Purity

Variant

GLP SM

Lot #

GLZ-GLP-1-SM-10MG-A

Labelled

10mg

Actual

15.18mg

Tested

12/12/2025

View COA

Frequently Asked Questions

Common questions about GLP-1 SM research

What is GLP-1 SM?

GLP-1 SM is a synthetic 31-amino acid peptide that mimics GLP-1, a hormone involved in blood sugar regulation and appetite control.

How is research-grade GLP-1 SM different from commercially available formulations?

Research-grade GLP-1 SM is a lyophilized peptide produced via chemical synthesis. It differs from FDA-approved pharmaceutical formulations in manufacturing process, purity profile, formulation, and delivery method. It is sold strictly for laboratory research purposes only.

How should GLP-1 SM be stored?

Lyophilized GLP-1 SM should be stored below -18°C, away from light and moisture. Once reconstituted, refrigerate at 2–8°C and use within 7 days.

What clinical trials have been conducted on GLP-1 SM ?

GLP-1 SM has been studied in extensive Phase III programs including SUSTAIN, STEP, PIONEER, and SELECT, covering diabetes, obesity, and cardiovascular outcomes.

Is research-grade GLP-1 SM FDA approved?

No. Research-grade semaglutide is not FDA approved and is not equivalent to approved drug products. It is sold for laboratory and research purposes only.

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GLP-1 SM

Description