Adipotide
-11%
4X Tested - ISO 17025
99.90% View COA
Metabolic Peptide

Adipotide

Certificate of Analysis

Adipotide (CKGGRAKDC-GG-D(KLAKLAK)2) is a peptidomimetic that targets the vascular supply of adipose tissue, studied in preclinical models for its effects on fat cell apoptosis and weight reduction.

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Description

What is Adipotide?

Adipotide is a synthetic peptidomimetic compound consisting of two functional domains: a targeting sequence (CKGGRAKDC) that binds to prohibitin, a receptor found on the blood vessels supplying white adipose tissue, and a pro-apoptotic sequence (D(KLAKLAK)2) that disrupts mitochondrial membranes.

By selectively targeting the vasculature of fat tissue, adipotide is designed to induce apoptosis (programmed cell death) in adipose tissue blood vessel cells, cutting off the blood supply to fat deposits. This approach represents a fundamentally different mechanism from other weight-management compounds.

In preclinical studies on obese primates, adipotide demonstrated significant reductions in body weight and improvements in insulin resistance. However, researchers noted reversible kidney-related effects that require further investigation.

Adipotide is an experimental compound not approved by any regulatory agency. It is sold strictly for laboratory and research purposes only.

Research Applications

Areas of Investigation
Fat Targeting

Targeted Adipose Vascular Disruption

Studied for its ability to selectively target blood vessels supplying white adipose tissue through prohibitin receptor binding.
Weight Loss

Weight Reduction Research

Demonstrated significant body weight reduction in obese primate models through adipose tissue blood supply disruption.
Metabolism

Insulin Sensitivity

Investigated for improvements in insulin resistance observed alongside weight reduction in primate studies.

Compound Profile

Technical specifications
What is Adipotide?

Molecular Profile

Sequence
CKGGRAKDC GG D (KLAKLAK)₂
Molecular Formula
Peptidomimetic (complex chimeric structure)
Molecular Weight
~2,500 g/mol (approximate)
Appearance
White lyophilized powder

Form

Lyophilized (freeze-dried)
Handling & Shelf Life Guidelines

Storage & Stability

Storage (Pre-Reconstitution)

Store below -20°C, desiccated, away from light and moisture.
Storage (Post-Reconstitution)
Refrigerate at 2–8°C. For longer storage, aliquot and store below -18°C. Avoid freeze-thaw cycles.
Shelf Life
24 months from date of manufacture when stored as directed
Sensitivity Notes
Sensitive to heat, light, and moisture. Keep sealed until use.
Compliance & Clinical Overview

Regulatory & Research Status

FDA Status
Not approved for human use. Experimental compound with limited safety data.
WADA Classification
Not specifically listed (experimental compound).
Clinical Trial Status
Published preclinical studies in obese rhesus monkeys showing weight reduction and metabolic improvements.
Published Studies
Published preclinical studies in obese rhesus monkeys showing weight reduction and metabolic improvements.
Research Disclaimer
Experimental research compound. For laboratory and research purposes only. Not intended for human consumption.

COA's (Certificate of Analysis)

Third Party Tested by Freedom Diagnostics
99.90%
Purity
Variant
Adipotide
Lot #
GL-2609-002
Labelled
10mg
Actual
10.43mg
Tested
9/24/2026
View COA
(opens in a new tab)
99.81%
Purity
Variant
Adipotide
Lot #
GLZ-ADIPOTIDE-10MG-A
Labelled
10mg
Actual
9.48mg
Tested
3/29/2026
View COA
(opens in a new tab)

Frequently Asked Questions

Common questions about Adipotide research